RESEARCH

Our lab studies how human development is shaped by multimodal regulation. What are the fundamental principles governing phenotypic, metabolic, and morphogenetic processes in early embryonic patterning? What are the causal mechanisms when these dynamic processes go awry? Our work represents a new paradigm in developmental biology, where traditional genetic-focused perspectives are enriched by a deeper understanding of the metabolic context driving these processes.

By combining studies of mouse and human embryos with in vitro 3D stem cell models, our laboratory explores the molecular landscape directing differentiation and developmental programming in both health and disease.