Selected Publications

Semin. Cell Dev. Bio | 2022  

Sozen B., Conkar D., Veenvliet V.J.

Carnegie in 4D? Stem-cell-based models of human embryo development

go to this paper

 

Nature Communications | 2021

Sozen B, Jorgensen V, Weatherbee B, Chen S, Zhu M, Zernicka-Goetz M.

Reconstructing aspects of human embryogenesis with pluripotent stem cells

 go to this paper 

 

 

Scientific Reports | 2021  

Okan A, Demir N, Sozen B.

Unfolded protein response triggers differential apoptotic mechanisms in ovaries and early embryos exposed to maternal type 1 diabetes

 go to this paper

 

Developmental Biology | 2021

Sozen B., Cornwall-Scoones J, Zernicka-Goetz M.

The dynamics of morphogenesis in stem cell-based embryology: Novel insights for symmetry breaking

 go to this paper 

*Cover image designed for the ‘Synthetic Embryology’ special issue

 

Developmental Cell | 2019  

Sozen B, Cox A, De Jonghe J, Bao M, Hollfelder F, Glover DM, Zernicka-Goetz M.

Self-organization of mouse stem cells into an extended potential blastoid.

 go to this paper

 

Nature Cell Biology | 2018

Sozen B, Amadei G, Cox A, Wang R, Na E, Czukiewska S, Chappell L, Voet T, Michel G, Jing N, Glover DM, Zernicka-Goetz M.

Self-assembly of embryonic and two extra-embryonic stem cell types into gastrulating embryo-like structures.

 go to this paper 

*Cover article

Research highlight in Nature Methods | Three tissues to gastrulation

Nature Protocols | 2018

Harrison S*, Sozen B*, Zernicka-Goetz M.

In vitro generation of mouse polarised embryo-like structures from embryonic and trophoblast stem cells.

 go to this paper 

Science | 2017                

Harrison S*, Sozen B*, Christodoulou N, Kyprianou C, Zernicka-Goetz M.

Assembly of embryonic and extraembryonic stem cells to mimic embryogenesis in vitro.

 go to this paper 

Commentaries:

Science | Embryogenesis in a dish (by Martin Pera)

Nature Methods | It takes two to make an embryo

Cell Research | Reassembling embryos in vitro from  component stem cells

Mech. of Development | 2015

Sozen B,  Ozturk S, Yaba A, Demir N.

The p38 MAPK pathway is required for glucose metabolism, lineage specification and embryo survival during mouse preimplantation development.

 go to this paper 

 

Developmental Biology | 2014

Sozen B, Can A, Demir N.

Cell fate regulation during preimplantation development: A view of adhesion-linked molecular interaction.

 go to this paper 

Fertility and Sterility | 2014

Basar M,  Bozkurt I, Guzeloglu-Kayisli O, Sozen B,  Tekmen I, Schatz F, Arici A, Lockwood CJ, Kayisli UA.

Unfolded protein response prevents blastocyst formation during preimplantation embryo development in vitro.

 go to this paper

 

Molecular Human Reproduction | 2014

Ozturk S, Sozen B, Demir N.

Telomere length and telomerase activity during oocyte maturation and early embryo development in mammalian species.

 go to this paper

Full list