Selected Publications

Developmental Cell | 2019  

Sozen B, Cox A, De Jonghe J, Bao M, Hollfelder F, Glover DM, Zernicka-Goetz M.

Self-organisation of mouse stem cells into an extended potential blastoid.

 

Nature Cell Biology | 2018

Sozen B, Amadei G, Cox A, Wang R, Na E, Czukiewska S, Chappell L, Voet T, Michel G, Jing N, Glover DM, Zernicka-Goetz M.

Self-assembly of embryonic and two extra-embryonic stem cell types into gastrulating embryo-like structures.

*Cover article

Research highlight in Nature Methods | Three tissues to gastrulation

Nature Protocols | 2018

Harrison S*, Sozen B*, Zernicka-Goetz M.

In vitro generation of mouse polarised embryo-like structures from embryonic and trophoblast stem cells.

 

Science | 2017                

Harrison S*, Sozen B*, Christodoulou N, Kyprianou C, Zernicka-Goetz M.

Assembly of embryonic and extraembryonic stem cells to mimic embryogenesis in vitro.

Commentaries:

Science | Embryogenesis in a dish (by Martin Pera)

Nature Methods | It takes two to make an embryo

Cell Research | Reassembling embryos in vitro from  component stem cells

Mech. of Development | 2015

Sozen B,  Ozturk S, Yaba A, Demir N.

The p38 MAPK pathway is required for glucose metabolism, lineage specification and embryo survival during mouse preimplantation development.

 

Developmental Biology | 2014

Sozen B, Can A, Demir N.

Cell fate regulation during preimplantation development: A view of adhesion-linked molecular interaction.

Fertility and Sterility | 2014

Basar M,  Bozkurt I, Guzeloglu-Kayisli O, Sozen B,  Tekmen I, Schatz F, Arici A, Lockwood CJ, Kayisli UA.

Unfolded protein response prevents blastocyst formation during preimplantation embryo development in vitro.

 

Molecular Human Reproduction | 2014

Ozturk S, Sozen B, Demir N.

Telomere length and telomerase activity during oocyte maturation and early embryo development in mammalian species.

 

Full list