Selected Publications

Nature | 2023  

Pedroza M.*, Gassaloglu SI.*, Dias N., Zhong L., Hou TJ., Kretzmer T., Smith ZD., Sozen B.

Self-patterning of human stem cells into post-implantation lineages

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*Cover article

*Nature Methods Method of the Year 2023

Biorxiv | 2023  

Cao D., Zhong L., Hemalatha A., Bergmann J., Cox A.L., Greco V., Sozen B.

A spatiotemporal compartmentalization of glucose metabolism guides mammalian gastrulation progression

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*Preprint highlight in Development

Curr. Opin. in Genetics & Development | 2023

Abel A., Sozen B.

Shifting early embryology paradigms: Applications of stem cell-based embryo models in bioengineering

*themed issue on Early embryonic developmental models

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Semin. Cell Dev. Bio | 2022  

Sozen B., Conkar D., Veenvliet V.J.

Carnegie in 4D? Stem-cell-based models of human embryo development

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Nature Communications | 2021

Sozen B, Jorgensen V, Weatherbee B, Chen S, Zhu M, Zernicka-Goetz M.

Reconstructing aspects of human embryogenesis with pluripotent stem cells

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Scientific Reports | 2021  

Okan A, Demir N, Sozen B.

Unfolded protein response triggers differential apoptotic mechanisms in ovaries and early embryos exposed to maternal type 1 diabetes

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Developmental Biology | 2021

Sozen B., Cornwall-Scoones J, Zernicka-Goetz M.

The dynamics of morphogenesis in stem cell-based embryology: Novel insights for symmetry breaking

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*Cover image designed for the ‘Synthetic Embryology’ special issue


Developmental Cell | 2019  

Sozen B, Cox A, De Jonghe J, Bao M, Hollfelder F, Glover DM, Zernicka-Goetz M.

Self-organization of mouse stem cells into an extended potential blastoid.

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Nature Cell Biology | 2018

Sozen B, Amadei G, Cox A, Wang R, Na E, Czukiewska S, Chappell L, Voet T, Michel G, Jing N, Glover DM, Zernicka-Goetz M.

Self-assembly of embryonic and two extra-embryonic stem cell types into gastrulating embryo-like structures.

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*Cover article

Research highlight in Nature Methods | Three tissues to gastrulation

Science | 2017                

Harrison S*, Sozen B*, Christodoulou N, Kyprianou C, Zernicka-Goetz M.

Assembly of embryonic and extraembryonic stem cells to mimic embryogenesis in vitro.

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Science | Embryogenesis in a dish (by Martin Pera)

Nature Methods | It takes two to make an embryo

Cell Research | Reassembling embryos in vitro from  component stem cells

Mech. of Development | 2015

Sozen B,  Ozturk S, Yaba A, Demir N.

The p38 MAPK pathway is required for glucose metabolism, lineage specification and embryo survival during mouse preimplantation development.

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Developmental Biology | 2014

Sozen B, Can A, Demir N.

Cell fate regulation during preimplantation development: A view of adhesion-linked molecular interaction.

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Full list